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The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.
Gerbino, Valeria; Kaunga, Esther; Ye, Junqiang; Canzio, Daniele; O'Keeffe, Sean; Rudnick, Noam D; Guarnieri, Paolo; Lutz, Cathleen M; Maniatis, Tom.
Afiliação
  • Gerbino V; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
  • Kaunga E; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
  • Ye J; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
  • Canzio D; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA.
  • O'Keeffe S; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
  • Rudnick ND; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
  • Guarnieri P; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA.
  • Lutz CM; The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
  • Maniatis T; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA; Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY 10027, USA; New York Genome Center, New York, NY 10013, USA; Vagelos College of Physicians and Surgeons, Colum
Neuron ; 106(5): 789-805.e5, 2020 06 03.
Article em En | MEDLINE | ID: mdl-32220666
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas Serina-Treonina Quinases / Microglia / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica / Neurônios Motores Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas Serina-Treonina Quinases / Microglia / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica / Neurônios Motores Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article