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Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells.
Quattrini, Luca; Gelardi, Edoardo Luigi Maria; Coviello, Vito; Sartini, Stefania; Ferraris, Davide Maria; Mori, Mattia; Nakano, Ichiro; Garavaglia, Silvia; La Motta, Concettina.
Afiliação
  • Quattrini L; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Gelardi ELM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
  • Coviello V; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Sartini S; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
  • Mori M; Department of Biotechnology, Chemistry and Pharmacy "Department of Excellence 2018-2022", University of Siena, via Aldo Moro 2, 53100 Siena, Italy.
  • Nakano I; Department of Neurosurgery, University of Alabama at Birmingham, WTI 401, 1824 Sixth Avenue South, Birmingham, Alabama 35233, United States.
  • Garavaglia S; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
  • La Motta C; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
J Med Chem ; 63(9): 4603-4616, 2020 05 14.
Article em En | MEDLINE | ID: mdl-32223240
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Células-Tronco Neoplásicas / Aldeído Oxirredutases / Inibidores Enzimáticos / Imidazóis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Células-Tronco Neoplásicas / Aldeído Oxirredutases / Inibidores Enzimáticos / Imidazóis Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article