Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient.
Proc Natl Acad Sci U S A
; 117(16): 8941-8947, 2020 04 21.
Article
em En
| MEDLINE
| ID: mdl-32241888
ABSTRACT
The bacterial flagellum is an amazing nanomachine. Understanding how such complex structures arose is crucial to our understanding of cellular evolution. We and others recently reported that in several Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persists in the outer membrane after flagellum disassembly. Imaging nine additional species with cryo-electron tomography, here, we show that this subcomplex persists after flagellum disassembly in other phyla as well. Bioinformatic analyses fail to show evidence of any recent horizontal transfers of the P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserved feature of the flagellar motor. We hypothesize that one function of the P and L rings is to seal the outer membrane after motor disassembly.
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MEDLINE
Assunto principal:
Bactérias
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Proteínas da Membrana Bacteriana Externa
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Proteínas de Bactérias
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Especiação Genética
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Flagelos
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article