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A model for the interplay between plastic tradeoffs and evolution in changing environments.
Tikhonov, Mikhail; Kachru, Shamit; Fisher, Daniel S.
Afiliação
  • Tikhonov M; Department of Physics, Washington University in St. Louis, St. Louis, MO 63130; tikhonov@wustl.edu.
  • Kachru S; Center for Science and Engineering of Living Systems, Washington University in St. Louis, St. Louis, MO 63130.
  • Fisher DS; Department of Physics, Stanford University, Stanford, CA 94305.
Proc Natl Acad Sci U S A ; 117(16): 8934-8940, 2020 04 21.
Article em En | MEDLINE | ID: mdl-32245811
Performance tradeoffs are ubiquitous in both ecological and evolutionary modeling, yet they are usually postulated and built into fitness and ecological landscapes. However, tradeoffs depend on genetic background and evolutionary history and can themselves evolve. We present a simple model capable of capturing the key feedback loop: evolutionary history shapes tradeoff strength, which, in turn, shapes evolutionary future. One consequence of this feedback is that genomes with identical fitness can have different evolutionary properties shaped by prior environmental exposure. Another is that, generically, the best adaptations to one environment may evolve in another. Our simple framework bridges the gap between the phenotypic Fisher's Geometric Model and the genotypic properties, such as modularity and evolvability, and can serve as a rich playground for investigating evolution in multiple or changing environments.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Fisiológica / Evolução Molecular / Interação Gene-Ambiente / Modelos Genéticos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Fisiológica / Evolução Molecular / Interação Gene-Ambiente / Modelos Genéticos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article