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Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling.
Huang, Jiaqi; Cai, Changhong; Zheng, Tianyu; Wu, Xinyan; Wang, Dongfei; Zhang, Kaijie; Xu, Bocheng; Yan, Ruochen; Gong, Hui; Zhang, Jie; Shi, Yueli; Xu, Zhiyong; Zhang, Xue; Zhang, Xuemin; Shang, Tao; Zhou, Jianhong; Guo, Xiaogang; Zeng, Chunlai; Lai, En Yin; Xiao, Changchun; Chen, Ju; Wan, Shu; Liu, Wen-Hsien; Ke, Yuehai; Cheng, Hongqiang.
Afiliação
  • Huang J; From the Department of Pathology and Pathophysiology and Department of Cardiology, Sir Run Run Shaw Hospital (J.H., K.Z., H.C.), Zhejiang University School of Medicine, Hangzhou, China.
  • Cai C; Department of Cardiology, Lishui Hospital, Zhejiang University School of Medicine, China. (C.C., C.Z.).
  • Zheng T; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Wu X; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Wang D; Department of Cardiovascular Science, The First Affiliated Hospital of Zhejiang University (D.W., X.G.), Zhejiang University School of Medicine, Hangzhou, China.
  • Zhang K; From the Department of Pathology and Pathophysiology and Department of Cardiology, Sir Run Run Shaw Hospital (J.H., K.Z., H.C.), Zhejiang University School of Medicine, Hangzhou, China.
  • Xu B; Institute of Feed Science, College of Animal Sciences, Zhejiang University, Hangzhou, China (B.X.).
  • Yan R; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Gong H; Key Laboratory for Translational Medicine, First Affiliated Hospital, Huzhou University, China (H.G.).
  • Zhang J; Department of Urology, Sir Run Run Shaw Hospital (J. Zhang), Zhejiang University School of Medicine, Hangzhou, China.
  • Shi Y; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Xu Z; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Zhang X; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
  • Zhang X; Department of Vascular Surgery, Peking University People's Hospital, Peking University Health Science Center, Peking University, Beijing, China (X. Zhang).
  • Shang T; Department of Vascular Surgery, The First Affiliated Hospital (T.S.).
  • Zhou J; Department of Gynecology, School of Medicine, Zhejiang University, Hangzhou, China (J. Zhou).
  • Guo X; Department of Cardiovascular Science, The First Affiliated Hospital of Zhejiang University (D.W., X.G.), Zhejiang University School of Medicine, Hangzhou, China.
  • Zeng C; Department of Cardiology, Lishui Hospital, Zhejiang University School of Medicine, China. (C.C., C.Z.).
  • Lai EY; Department of Physiology, School of Basic Medical Sciences (E.Y.L.), Zhejiang University School of Medicine, Hangzhou, China.
  • Xiao C; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, China (C.X., W.-H.L.).
  • Chen J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA (C.X.).
  • Wan S; Department of Medicine and Cardiology, University of California San Diego, La Jolla (J.C.).
  • Liu WH; Brain Center of Zhejiang Hospital, Hangzhou, China (S.W.).
  • Ke Y; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, China (C.X., W.-H.L.).
  • Cheng H; Department of Pathology and Pathophysiology (T.Z., X. Wu, R.Y., Y.S., Z.X., X.Z., Y.K.), Zhejiang University School of Medicine, Hangzhou, China.
Arterioscler Thromb Vasc Biol ; 40(7): 1705-1721, 2020 07.
Article em En | MEDLINE | ID: mdl-32268790
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artéria Carótida Primitiva / Fosfoproteínas Fosfatases / Lesões das Artérias Carótidas / Proteínas Adaptadoras de Transdução de Sinal / Óxido Nítrico Sintase Tipo III / Proteínas Proto-Oncogênicas c-akt / Remodelação Vascular / Proteínas dos Microfilamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artéria Carótida Primitiva / Fosfoproteínas Fosfatases / Lesões das Artérias Carótidas / Proteínas Adaptadoras de Transdução de Sinal / Óxido Nítrico Sintase Tipo III / Proteínas Proto-Oncogênicas c-akt / Remodelação Vascular / Proteínas dos Microfilamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article