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A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism.
Sobotta, Jessica; Geisberger, Thomas; Moosmann, Carolin; Scheidler, Christopher M; Eisenreich, Wolfgang; Wächtershäuser, Günter; Huber, Claudia.
Afiliação
  • Sobotta J; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
  • Geisberger T; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
  • Moosmann C; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
  • Scheidler CM; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
  • Eisenreich W; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
  • Wächtershäuser G; 209 Mill Race Drive, Chapel Hill, NC 27514, USA.
  • Huber C; Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany.
Life (Basel) ; 10(4)2020 Apr 07.
Article em En | MEDLINE | ID: mdl-32272667
Carbon fixation, in addition to the evolution of metabolism, is a main requirement for the evolution of life. Here, we report a one-pot carbon fixation of acetylene (C2H2) and carbon monoxide (CO) by aqueous nickel sulfide (NiS) under hydrothermal (>100 °C) conditions. A slurry of precipitated NiS converts acetylene and carbon monoxide into a set of C2-4-products that are surprisingly representative for C2-4-segments of all four central CO2-fixation cycles of the domains Bacteria and Archaea, whereby some of the products engage in the same interconversions, as seen in the central CO2-fixation cycles. The results suggest a primordial, chemically predetermined, non-cyclic acetyleno/carboxydotrophic core metabolism. This metabolism is based on aqueous organo-metal chemistry, from which the extant central CO2-fixation cycles based on thioester chemistry would have evolved by piecemeal modifications.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article