Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas.

Dietz, Matthew S; Beach, Catherine Z; Barajas, Ramon; Parappilly, Michael S; Sengupta, Sidharth K; Baird, Lissa C; Ciporen, Jeremy N; Han, Seunggu J; Loret de Mola, Rebecca; Cho, Yoon Jae; Nazemi, Kellie J; McClelland, Shearwood; Wong, Melissa H; Jaboin, Jerry J.

Afiliação

Dietz MS; Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
Beach CZ; Department of Radiation Medicine, Oregon Health & Science University, Portland, Oregon.
Barajas R; Department of Diagnostic Radiology, Oregon Health & Science University, Portland, Oregon.
Parappilly MS; Advanced Imaging Research Center, Oregon Health & Science University, Portland, Oregon.
Sengupta SK; Department of Diagnostic Radiology, Oregon Health & Science University, Portland, Oregon.
Baird LC; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, Oregon.
Ciporen JN; Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon.
Han SJ; Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon.
Loret de Mola R; Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon.
Cho YJ; Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
Nazemi KJ; Department of Neurology, Oregon Health & Science University, Portland, Oregon.
McClelland S; The Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon.
Wong MH; Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
Jaboin JJ; Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana.

Adv Radiat Oncol ; 5(2): 152-162, 2020.

Article em En | MEDLINE | ID: mdl-32280814

ABSTRACT

PURPOSE:

To review and critique the current state of liquid biopsy in pHGG. MATERIALS AND

Published literature was reviewed for articles related to liquid biopsy in pediatric glioma and adult glioma with a focus on high-grade gliomas.

This review discusses the current state of liquid biomarkers of pHGG and their potential applications for liquid biopsy development.

While nascent, the progress toward identifying circulating analytes of pHGG primes the field of neuro-oncoogy for liquid biopsy development.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article