The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection.

Kurtz, Sherry L; Rossi, Amy P; Beamer, Gillian L; Gatti, Dan M; Kramnik, Igor; Elkins, Karen L

Kurtz, Sherry L; Rossi, Amy P; Beamer, Gillian L; Gatti, Dan M; Kramnik, Igor; Elkins, Karen L.

Afiliação

Kurtz SL; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA sherry.kurtz@fda.hhs.gov karen.elkins@fda.hhs.gov.
Rossi AP; University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Beamer GL; Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts, USA.
Gatti DM; College of the Atlantic, Bar Harbor, Maine, USA.
Kramnik I; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Elkins KL; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA sherry.kurtz@fda.hhs.gov karen.elkins@fda.hhs.gov.

mSphere ; 5(2)2020 04 15.

Article em En | MEDLINE | ID: mdl-32295871

Assuntos

Camundongos de Cruzamento Colaborativo/microbiologia; Modelos Animais de Doenças; Vacinas contra a Tuberculose/imunologia; Tuberculose/genética; Tuberculose/imunologia; Animais; Camundongos de Cruzamento Colaborativo/imunologia; Feminino; Variação Genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Mycobacterium tuberculosis; Tuberculose/prevenção & controle; Vacinação

Palavras-chave

Diversity Outbred; Mycobacterium tuberculosis; animal models; immunization; tuberculosis vaccines; vaccines

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Vacinas contra a Tuberculose / Modelos Animais de Doenças / Camundongos de Cruzamento Colaborativo Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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