Follicular lymphoma generating in a patient with non-small cell lung cancer following nivolumab discontinuation.
J Oncol Pharm Pract
; 26(8): 2042-2046, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-32299317
ABSTRACT
INTRODUCTION:
Immune checkpoint inhibitors have demonstrated the benefit for many cancer types, melanoma, non-small cell lung cancer, urothelial cancer, renal cell cancer, etc. Especially in advanced non-small cell lung cancer, significant improvement in survival results has been shown. CASE REPORT Here, we report a 66-year-old man with lung adenocarcinoma who received nivolumab for 80 cycles.Management andOutcome:
Two months after discontinuing nivolumab, he developed follicular lymphoma. Pneumonitis was also accompanied, which was treated with metilprednisolon, but he died due to progressive respiratory failure.DISCUSSION:
Our clinical knowledge with checkpoint inhibitors is increasing day by day, and to the best of our knowledge, this paper presents the first case in the English literature who developed follicular lymphoma after discontinuing nivolumab in non-small cell lung cancer patient.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Linfoma Folicular
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Carcinoma Pulmonar de Células não Pequenas
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Nivolumabe
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Inibidores de Checkpoint Imunológico
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Neoplasias Pulmonares
Limite:
Aged
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article