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Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1.
Kowalski, John P; McDonald, Matthew G; Pelletier, Robert D; Hanenberg, Helmut; Wiek, Constanze; Rettie, Allan E.
Afiliação
  • Kowalski JP; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington 98105, United States.
  • McDonald MG; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington 98105, United States.
  • Pelletier RD; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington 98105, United States.
  • Hanenberg H; Department of Pediatrics III, University Children's Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
  • Wiek C; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, 40225 Düsseldorf, Germany.
  • Rettie AE; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington 98105, United States.
J Med Chem ; 63(9): 4824-4836, 2020 05 14.
Article em En | MEDLINE | ID: mdl-32302132
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Ácidos Graxos / Inibidores das Enzimas do Citocromo P-450 / Família 4 do Citocromo P450 Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triazóis / Ácidos Graxos / Inibidores das Enzimas do Citocromo P-450 / Família 4 do Citocromo P450 Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article