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COVID-19 Associated Hepatitis Complicating Recent Living Donor Liver Transplantation.
Lagana, Stephen M; De Michele, Simona; Lee, Michael J; Emond, Jean C; Griesemer, Adam D; Tulin-Silver, Sheryl A; Verna, Elizabeth C; Martinez, Mercedes; Lefkowitch, Jay H.
Afiliação
  • Lagana SM; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • De Michele S; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Lee MJ; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Emond JC; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Griesemer AD; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Tulin-Silver SA; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Verna EC; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Martinez M; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
  • Lefkowitch JH; Department of Pathology and Cell Biology (Dr. Lagana, Dr. De Michele, Dr. Lee, Dr. Lefkowitch); Department of Surgery (Dr. Emond, Dr. Griesemer); Department of Radiology (Dr Tulin-Silver); Department of Medicine Digestive and Liver Disease (Dr. Verna); Department of Pediatrics (Dr. Martinez), at the
Arch Pathol Lab Med ; 2020 Apr 17.
Article em En | MEDLINE | ID: mdl-32302212
ABSTRACT
We present a case of COVID-19 hepatitis in a living donor liver allograft recipient whose donor subsequently tested positive for COVID-19. The patient is a female infant with biliary atresia (failed Kasai procedure). She recovered well, with improving liver function tests for 4 days. On post-operative day (POD) 4 the patient developed respiratory distress and fever. COVID-19 testing (polymerase chain reaction) was positive. Liver function tests increased approximately 5-fold. Liver biopsy showed moderate acute hepatitis with prominent clusters of apoptotic hepatocytes and associated cellular debris. Lobular lymphohistiocytic inflammation was noted. Typical portal features of mild to moderate acute cellular rejection were also noted.

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article