Are immune-related adverse events associated with the efficacy of immune checkpoint inhibitors in patients with cancer? A systematic review and meta-analysis.

Zhou, Xiaoxiang; Yao, Zhuoran; Yang, Huaxia; Liang, Naixin; Zhang, Xuan; Zhang, Fengchun

Zhou, Xiaoxiang; Yao, Zhuoran; Yang, Huaxia; Liang, Naixin; Zhang, Xuan; Zhang, Fengchun.

Afiliação

Zhou X; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, The Ministry of Education Key Laboratory, Beijing, 100730, China.
Yao Z; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, The Ministry of Education Key Laboratory, Beijing, 100730, China.
Yang H; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, The Ministry of Education Key Laboratory, Beijing, 100730, China. yanghuaxia2013@163.com.
Liang N; Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, 100730, China. pumchnelson@163.com.
Zhang X; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, The Ministry of Education Key Laboratory, Beijing, 100730, China.
Zhang F; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, The Ministry of Education Key Laboratory, Beijing, 100730, China.

BMC Med ; 18(1): 87, 2020 04 20.

Article em En | MEDLINE | ID: mdl-32306958

Assuntos

Anticorpos Monoclonais/efeitos adversos; Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/imunologia; Neoplasias/tratamento farmacológico; Humanos; Neoplasias/complicações

Palavras-chave

Cancer; Efficacy; Immune checkpoint inhibitors; Immune-related adverse events

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Anticorpos Monoclonais / Neoplasias Tipo de estudo: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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