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How do cyclic antibiotics with activity against Gram-negative bacteria permeate membranes? A machine learning informed experimental study.
Lee, Michelle W; de Anda, Jaime; Kroll, Carsten; Bieniossek, Christoph; Bradley, Kenneth; Amrein, Kurt E; Wong, Gerard C L.
Afiliação
  • Lee MW; Department of Bioengineering, Department of Chemistry, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, United States.
  • de Anda J; Department of Bioengineering, Department of Chemistry, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, United States.
  • Kroll C; Roche Pharma Research and Early Development Pharmaceutical Science, Roche, Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Bieniossek C; Roche Pharma Research and Early Development Pharmaceutical Science, Roche, Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Bradley K; Roche Pharma Research and Early Development Pharmaceutical Science, Roche, Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Amrein KE; Roche Pharma Research and Early Development Pharmaceutical Science, Roche, Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Wong GCL; Department of Bioengineering, Department of Chemistry, California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, United States. Electronic address: gclwong@seas.ucla.edu.
Biochim Biophys Acta Biomembr ; 1862(8): 183302, 2020 08 01.
Article em En | MEDLINE | ID: mdl-32311341
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Permeabilidade da Membrana Celular / Peptídeos Catiônicos Antimicrobianos / Bactérias Gram-Negativas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Permeabilidade da Membrana Celular / Peptídeos Catiônicos Antimicrobianos / Bactérias Gram-Negativas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article