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Synthesis and cytotoxic effects of 2-thio-3,4-dihydroquinazoline derivatives as novel T-type calcium channel blockers.
Nam, Yunchan; Ryu, Ki Deok; Jang, Changyoung; Moon, Yoon Hyoung; Kim, Misong; Ko, Dohyeong; Chung, Kyung-Sook; Gandini, Maria A; Lee, Kyung-Tae; Zamponi, Gerald W; Lee, Jae Yeol.
Afiliação
  • Nam Y; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Ryu KD; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Jang C; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Moon YH; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Kim M; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Ko D; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Chung KS; Department of Life and Nanopharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
  • Gandini MA; Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary T2N 4N1, Canada.
  • Lee KT; Department of Life and Nanopharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address: ktlee@khu.ac.kr.
  • Zamponi GW; Department of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary T2N 4N1, Canada. Electronic address: zamponi@ucalgary.ca.
  • Lee JY; Research Institute for Basic Sciences and Department of Chemistry, College of Sciences, Kyung Hee University, Seoul 02447, Republic of Korea; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address: ljy@khu.ac.kr.
Bioorg Med Chem ; 28(11): 115491, 2020 06 01.
Article em En | MEDLINE | ID: mdl-32327350
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Bloqueadores dos Canais de Cálcio / Canais de Cálcio Tipo T / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Bloqueadores dos Canais de Cálcio / Canais de Cálcio Tipo T / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article