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Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis.
Shao, Chenwen; Yuan, Jiwen; Liu, Yani; Qin, Yajuan; Wang, Xueao; Gu, Jin; Chen, Guiquan; Zhang, Bing; Liu, Hong-Ke; Zhao, Jing; Zhu, Hai-Liang; Qian, Yong.
Afiliação
  • Shao C; School of Chemistry and Materials Science, Nanjing Normal University, 210046 Nanjing, China.
  • Yuan J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China.
  • Liu Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China.
  • Qin Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China.
  • Wang X; School of Pharmacy, Nanjing Medical University, 211166 Nanjing, China.
  • Gu J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China.
  • Chen G; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China.
  • Zhang B; State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Nanjing University, 210061 Nanjing, China.
  • Liu HK; Department of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 210008 Nanjing, China.
  • Zhao J; School of Chemistry and Materials Science, Nanjing Normal University, 210046 Nanjing, China.
  • Zhu HL; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China; jingzhao@nju.edu.cn zhuhl@nju.edu.cn.
  • Qian Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023 Nanjing, China; jingzhao@nju.edu.cn zhuhl@nju.edu.cn.
Proc Natl Acad Sci U S A ; 117(19): 10155-10164, 2020 05 12.
Article em En | MEDLINE | ID: mdl-32327603
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Ácido Hipocloroso / Peroxidase / Estresse Oxidativo / Apigenina / Epilepsia / Ferroptose Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Ácido Hipocloroso / Peroxidase / Estresse Oxidativo / Apigenina / Epilepsia / Ferroptose Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article