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RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models.
Haase, Nadine; Foster, Donald J; Cunningham, Mark W; Bercher, Julia; Nguyen, Tuyen; Shulga-Morskaya, Svetlana; Milstein, Stuart; Shaikh, Sarfraz; Rollins, Jeff; Golic, Michaela; Herse, Florian; Kräker, Kristin; Bendix, Ivo; Serdar, Meray; Napieczynska, Hanna; Heuser, Arnd; Gellhaus, Alexandra; Thiele, Kristin; Wallukat, Gerd; Müller, Dominik N; LaMarca, Babbette; Dechend, Ralf.
Afiliação
  • Haase N; Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Foster DJ; Charité - Universitätsmedizin Berlin, Berlin Germany.
  • Cunningham MW; Experimental and Clinical Research Center, Berlin, Germany.
  • Bercher J; DZHK (German Centre for Cardiovascular Research), Berlin, Germany.
  • Nguyen T; Berlin Institute of Health (BIH), Berlin, Germany.
  • Shulga-Morskaya S; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Milstein S; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
  • Shaikh S; Experimental and Clinical Research Center, Berlin, Germany.
  • Rollins J; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Golic M; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Herse F; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Kräker K; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Bendix I; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Serdar M; Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Napieczynska H; Charité - Universitätsmedizin Berlin, Berlin Germany.
  • Heuser A; Experimental and Clinical Research Center, Berlin, Germany.
  • Gellhaus A; Berlin Institute of Health (BIH), Berlin, Germany.
  • Thiele K; Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Wallukat G; Charité - Universitätsmedizin Berlin, Berlin Germany.
  • Müller DN; Experimental and Clinical Research Center, Berlin, Germany.
  • LaMarca B; Berlin Institute of Health (BIH), Berlin, Germany.
  • Dechend R; Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
J Clin Invest ; 130(6): 2928-2942, 2020 06 01.
Article em En | MEDLINE | ID: mdl-32338644
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Angiotensinogênio / Interferência de RNA Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pré-Eclâmpsia / Angiotensinogênio / Interferência de RNA Limite: Animals / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article