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Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria.
Cheng, Xiao-Yu; Biswas, Sangita; Li, Juan; Mao, Cheng-Jie; Chechneva, Olga; Chen, Jing; Li, Kai; Li, Jiao; Zhang, Jin-Ru; Liu, Chun-Feng; Deng, Wen-Bin.
Afiliação
  • Cheng XY; Department of Neurology and Suzhou Clinical Research of Neurological Diseases, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
  • Biswas S; Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, 95817, USA.
  • Li J; Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, 95817, USA.
  • Mao CJ; Shriners Hospital for Children of Northern California, Sacramento, CA, 95817, USA.
  • Chechneva O; School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, China.
  • Chen J; Key Laboratory of Hui Medicine Modernization, Ministry of Education, Yinchuan, 750004, China.
  • Li K; Department of Neurology and Suzhou Clinical Research of Neurological Diseases, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
  • Li J; Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, 95817, USA.
  • Zhang JR; Department of Neurology and Suzhou Clinical Research of Neurological Diseases, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
  • Liu CF; Department of Neurology and Suzhou Clinical Research of Neurological Diseases, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
  • Deng WB; Department of Neurology and Suzhou Clinical Research of Neurological Diseases, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Transl Neurodegener ; 9(1): 13, 2020 04 24.
Article em En | MEDLINE | ID: mdl-32345341
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rotenona / Astrócitos / Células-Tronco Pluripotentes Induzidas / Neurônios Dopaminérgicos / Inseticidas / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rotenona / Astrócitos / Células-Tronco Pluripotentes Induzidas / Neurônios Dopaminérgicos / Inseticidas / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article