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Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study.
Tantawy, Mohamed A; El-Sherbeeny, Nagla A; Helmi, Nawal; Alazragi, Reem; Salem, Neveen; Elaidy, Samah M.
Afiliação
  • Tantawy MA; Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Giza, 12622, Egypt. Mohamed_tantawy@daad-alumni.de.
  • El-Sherbeeny NA; Hormones Department, Medical Research Division, National Research Centre, Dokki, Giza, 12622, Egypt. Mohamed_tantawy@daad-alumni.de.
  • Helmi N; Medical School of Hannover, Hannover, Germany. Mohamed_tantawy@daad-alumni.de.
  • Alazragi R; Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt.
  • Salem N; Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
  • Elaidy SM; Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.
Mol Cell Biochem ; 469(1-2): 143-157, 2020 Jun.
Article em En | MEDLINE | ID: mdl-32356241
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Neoplasias Colorretais / Proteína Supressora de Tumor p53 / Interleucina-6 / Apoptose / Fator de Transcrição STAT3 / Janus Quinase 2 / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Neoplasias Colorretais / Proteína Supressora de Tumor p53 / Interleucina-6 / Apoptose / Fator de Transcrição STAT3 / Janus Quinase 2 / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article