Characterization of Black Pigmenturia in a Cat with Apocrine Gland Cystadenocarcinoma.
J Comp Pathol
; 176: 145-150, 2020 Apr.
Article
em En
| MEDLINE
| ID: mdl-32359628
ABSTRACT
An 8-year-old neutered female domestic shorthair cat was presented for further management of an apocrine gland cystadenocarcinoma. Extensive nodal metastasis was diagnosed and the cat was humanely destroyed 2 months after presentation. Post-mortem histopathology of the cystadenocarcinoma revealed areas of yellow-brown granular pigmentation on light microscopy, staining positively for reducing substances with Schmorl's stain and demonstrating autofluorescence on confocal microscopy. The cat's urine was black and also exhibited autofluorescence, and further analysis revealed increased free pentosidine. Based on these findings, it was presumed that the apocrine gland cystadenocarcinoma was producing lipofuscin-like pigments and that the characteristics of the urine were at least partially secondary to advanced glycation end-products.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Glândulas Apócrinas
/
Neoplasias das Glândulas Sudoríparas
/
Doenças do Gato
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Cistadenocarcinoma
Limite:
Animals
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article