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Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals.
Qin, Tian; Prins, Samantha; Groeneveld, Geert Jan; Van Westen, Gerard; de Vries, Helga E; Wong, Yin Cheong; Bischoff, Luc J M; de Lange, Elizabeth C M.
Afiliação
  • Qin T; Predictive Pharmacology, Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre of Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
  • Prins S; Centre for Human Drug Research (CHDR), 2333 CL Leiden, The Netherlands.
  • Groeneveld GJ; Centre for Human Drug Research (CHDR), 2333 CL Leiden, The Netherlands.
  • Van Westen G; Computational Drug Discovery, Division of Drug Discovery and Safety, Leiden Academic Centre of Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
  • de Vries HE; Neuro-immunology research group, Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Amsterdam UMC, 1081 HZ Amsterdam, The Netherlands.
  • Wong YC; Advanced Modelling and Simulation, UCB Celltech, Slough SL1 3WE, UK.
  • Bischoff LJM; Predictive Pharmacology, Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre of Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
  • de Lange ECM; Predictive Pharmacology, Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre of Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
Int J Mol Sci ; 21(9)2020 Apr 30.
Article em En | MEDLINE | ID: mdl-32365768

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Animais de Doenças / Suscetibilidade a Doenças / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Animais de Doenças / Suscetibilidade a Doenças / Doença de Alzheimer Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article