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HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Kogler, Melanie; Tortola, Luigi; Negri, Gian Luca; Leopoldi, Alexandra; El-Naggar, Amal M; Mereiter, Stefan; Gomez-Diaz, Carlos; Nitsch, Roberto; Tortora, Davide; Kavirayani, Anoop M; Gapp, Bianca V; Rao, Shuan; Uribesalgo, Iris; Hoffmann, David; Cikes, Domagoj; Novatchkova, Maria; Williams, David A; Trent, Jeffrey M; Ikeda, Fumiyo; Daugaard, Mads; Hagelkruys, Astrid; Sorensen, Poul H; Penninger, Josef M.
Afiliação
  • Kogler M; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Tortola L; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria. josef.penninger@ubc.ca luigi.tortola@biol.ethz.ch.
  • Negri GL; Institute of Molecular Health Sciences, Department of Biology, ETH Zurich, Switzerland.
  • Leopoldi A; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • El-Naggar AM; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Mereiter S; Michael Smith Genome Sciences Centre, Vancouver, British Columbia, Canada.
  • Gomez-Diaz C; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Nitsch R; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Tortora D; Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
  • Kavirayani AM; Department of Pathology, Faculty of Medicine, Menoufia University, Menoufia Governorate, Egypt.
  • Gapp BV; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Rao S; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Uribesalgo I; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Hoffmann D; Advanced Medicines Safety, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Cikes D; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
  • Novatchkova M; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
  • Williams DA; Vienna BioCentre Core Facilities, Vienna BioCentre, Vienna, Austria.
  • Trent JM; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Ikeda F; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Daugaard M; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Hagelkruys A; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Sorensen PH; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCentre, Vienna, Austria.
  • Penninger JM; Research Institute of Molecular Pathology, Vienna BioCentre, Vienna, Austria.
Cancer Res ; 80(14): 3009-3022, 2020 07 15.
Article em En | MEDLINE | ID: mdl-32366477
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Proteínas rac de Ligação ao GTP / Proteínas rac1 de Ligação ao GTP / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Carcinogênese / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Proteínas rac de Ligação ao GTP / Proteínas rac1 de Ligação ao GTP / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Carcinogênese / Neoplasias Pulmonares Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article