Regulatory roles of ginseng on inflammatory caspases, executioners of inflammasome activation.
J Ginseng Res
; 44(3): 373-385, 2020 May.
Article
em En
| MEDLINE
| ID: mdl-32372859
AIM2, Absent in melanoma 2; ASC, Apoptosis-associated speck-like protein containing CARD; CARD, C-terminal caspase recruit domain; COX-2, Cyclooxygenase-2; Caspase, Cysteine aspartatespecific protease; DAMP, Danger-associated molecular pattern; FIIND, Functional-to-find domain; GSDMD, Gasdermin D; Ginseng; Ginsenoside; HIN, Hematopoietic interferon-inducible nuclear protein; IL, Interleukin; Inflammasome; Inflammation; Inflammatory caspase; LPS, Lipopolysaccharide; LRR, Leucine-rich repeat; NACHT, Nucleotide-binding and oligomerization domain; NF-κB, Nuclear factor-kappa B; NLR, Nucleotide-binding oligomerization domain-like receptor; NO, Nitric oxide; PAMP, Pathogen-associated molecular pattern; PGE2, Prostaglandin E2; PRR, Pattern-recognition receptor; PYD, N-terminal pyrin domain; RGE, Korean Red Ginseng; ROS, Reactive oxygen species
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