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Prodrugs of γ-Alkyl-Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase.
Zhao, Chenglong; Weber, Stefan; Schols, Dominique; Balzarini, Jan; Meier, Chris.
Afiliação
  • Zhao C; Organic Chemistry, Department of Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
  • Weber S; Organic Chemistry, Department of Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
  • Schols D; Laboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Balzarini J; Laboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Meier C; Organic Chemistry, Department of Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany.
Angew Chem Int Ed Engl ; 59(49): 22063-22071, 2020 12 01.
Article em En | MEDLINE | ID: mdl-32379948

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polifosfatos / Pró-Fármacos / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Transcriptase Reversa do HIV / Nucleosídeos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polifosfatos / Pró-Fármacos / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Transcriptase Reversa do HIV / Nucleosídeos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article