Importance of the fatty acid chain length on in vitro and in vivo anticancer activity of fattigation-platform albumin nanoparticles in human colorectal cancer xenograft mice model.

Park, Chulhun; Baek, Namhyun; Loebenberg, Raimar; Lee, Beom-Jin

Park, Chulhun; Baek, Namhyun; Loebenberg, Raimar; Lee, Beom-Jin.

Afiliação

Park C; College of Pharmacy, Ajou University, Suwon 16499, Republic of Korea; Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada. Electronic address: chulhun@ualberta.ca.
Baek N; Formulation Research Lab. DONG-WHA PHARM. Research Institute, Yongin 17084, Republic of Korea. Electronic address: namhyun.baek@dong-wha.co.kr.
Loebenberg R; Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2E1, Canada. Electronic address: raimar@ualberta.ca.
Lee BJ; College of Pharmacy, Ajou University, Suwon 16499, Republic of Korea; Institute of Pharmaceutical Science and Technology, Ajou University, Suwon 16499, Republic of Korea. Electronic address: bjl@ajou.ac.kr.

J Control Release ; 324: 55-68, 2020 08 10.

Article em En | MEDLINE | ID: mdl-32380202

Assuntos

Neoplasias Colorretais; Nanopartículas; Albuminas; Animais; Neoplasias Colorretais/tratamento farmacológico; Doxorrubicina; Portadores de Fármacos; Sistemas de Liberação de Medicamentos; Ácidos Graxos; Xenoenxertos; Humanos; Camundongos; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Doxorubicin; Fattigation-platform; Fatty acid chain length; Fatty acid-conjugated albumin nanoparticles; HCT116 cancer cells; Human colorectal cancer xenograft mice model

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Nanopartículas Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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