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[A Case of Neuroendocrine Carcinoma Treated with Salvage Surgery after Systemic Chemotherapy].
Nakano, Yusuke; Miyazaki, Yasuhiro; Nakatsuka, Rie; Motoori, Masaaki; Nishizawa, Yujiro; Komatsu, Hisateru; Inoue, Akira; Tomokuni, Akira; Komori, Takamichi; Fujitani, Kazumasa.
Afiliação
  • Nakano Y; Dept. of Gastroenterological Surgery, Osaka General Medical Center.
Gan To Kagaku Ryoho ; 47(2): 358-360, 2020 Feb.
Article em Ja | MEDLINE | ID: mdl-32381988
A man in his 50s was admitted to our hospital due to hematemesis.Esophagogastroduodenoscopy revealed an 8 cm type 2 gastric tumor.The tumor was histologically diagnosed as a neuroendocrine carcinoma.CT showed that the tumor had directly infiltrated the liver but there was no distant metastasis.We performed open distal gastrectomy, D2 lymph node dissection, partial hepatectomy, and cholecystectomy.Four months after the surgery, metastases of the right adrenal gland and dorsal part of the inferior vena cava were found.Although a significant tumor reduction was obtained by 12 courses of chemotherapy with CDDP plus CPT-11, this effective treatment was discontinued for the patient's convenience.Fifteen months after the surgery, metastasis of the right adrenal gland and dorsal part of inferior vena cava demonstrated re-growth without any further metastasis.After 4 courses of the same regimen, a partial response was obtained for the recurrences.As a salvage surgery, we performed open right adrenal gland and the lymph nodes of dorsal of IVC resection.The patient is alive without recurrence 1 year after the salvage surgery.
Assuntos
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Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Terapia de Salvação / Carcinoma Neuroendócrino Limite: Humans / Male / Middle aged Idioma: Ja Ano de publicação: 2020 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Terapia de Salvação / Carcinoma Neuroendócrino Limite: Humans / Male / Middle aged Idioma: Ja Ano de publicação: 2020 Tipo de documento: Article