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Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.
Clegg, Michael A; Bamborough, Paul; Chung, Chun-Wa; Craggs, Peter D; Gordon, Laurie; Grandi, Paola; Leveridge, Melanie; Lindon, Matthew; Liwicki, Gemma M; Michon, Anne-Marie; Molnar, Judit; Rioja, Inmaculada; Soden, Peter E; Theodoulou, Natalie H; Werner, Thilo; Tomkinson, Nicholas C O; Prinjha, Rab K; Humphreys, Philip G.
Afiliação
  • Clegg MA; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Bamborough P; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
  • Chung CW; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Craggs PD; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Gordon L; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Grandi P; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Leveridge M; Cellzome GmbH, R&D MST GlaxoSmithKline, Meyerhofstrasse 1 69117 Heidelberg, Germany.
  • Lindon M; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Liwicki GM; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Michon AM; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Molnar J; Cellzome GmbH, R&D MST GlaxoSmithKline, Meyerhofstrasse 1 69117 Heidelberg, Germany.
  • Rioja I; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Soden PE; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Theodoulou NH; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Werner T; GlaxoSmithKline R&D, Stevenage SG1 2NY, Hertfordshire, United Kingdom.
  • Tomkinson NCO; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
  • Prinjha RK; Cellzome GmbH, R&D MST GlaxoSmithKline, Meyerhofstrasse 1 69117 Heidelberg, Germany.
  • Humphreys PG; WestCHEM, Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, United Kingdom.
J Med Chem ; 63(11): 5816-5840, 2020 06 11.
Article em En | MEDLINE | ID: mdl-32410449
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridazinas / Fatores de Transcrição / Proteínas Cromossômicas não Histona / Lisina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridazinas / Fatores de Transcrição / Proteínas Cromossômicas não Histona / Lisina Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article