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Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21.
Hussain, Ali; Voisin, Veronique; Poon, Stephanie; Karamboulas, Christina; Bui, Ngoc Hoang Bao; Meens, Jalna; Dmytryshyn, Julia; Ho, Victor W; Tang, Kwan Ho; Paterson, Joshua; Clarke, Blaise A; Bernardini, Marcus Q; Bader, Gary D; Neel, Benjamin G; Ailles, Laurie E.
Afiliação
  • Hussain A; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Voisin V; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Poon S; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Karamboulas C; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Bui NHB; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Meens J; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Dmytryshyn J; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Ho VW; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Tang KH; Laura and Isaac Perlmutter Cancer Center, New York Langone Health, New York, NY.
  • Paterson J; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Clarke BA; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
  • Bernardini MQ; Department of Pathology, University Health Network, Toronto, Ontario, Canada.
  • Bader GD; Division of Gynaecologic Oncology, University Health Network, Toronto, Ontario, Canada.
  • Neel BG; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Ailles LE; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
J Exp Med ; 217(8)2020 08 03.
Article em En | MEDLINE | ID: mdl-32434219
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Resistencia a Medicamentos Antineoplásicos / Proliferação de Células / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Microambiente Tumoral / Fibroblastos Associados a Câncer / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Resistencia a Medicamentos Antineoplásicos / Proliferação de Células / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Microambiente Tumoral / Fibroblastos Associados a Câncer / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article