Cytotoxic jatrophane diterpenoids from the aerial parts of Euphorbia helioscopia.
J Asian Nat Prod Res
; 23(8): 731-737, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-32441128
ABSTRACT
A phytochemical study of 80% ethanol extract from the aerial parts of Euphorbia helioscopia led to the isolation of three new jatrophane diterpenoids, euphoheliphanes A-C (1-3). Their structures were established on the basis of spectroscopic data (NMR, IR, UV, and MS). The isolated diterpenoids were tested in vitro for cytotoxic potentials against 6 renal cancer cell lines. As a result, compounds 1-3 exhibited some cytotoxic activities against all the tested tumor cell lines with IC50 values less than 50 µM.[Formula see text].
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Base de dados:
MEDLINE
Assunto principal:
Euphorbia
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Diterpenos
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Antineoplásicos Fitogênicos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article