A strategy for large-scale comparison of evolutionary- and reaction-based classifications of enzyme function.

Holliday, Gemma L; Brown, Shoshana D; Mischel, David; Polacco, Benjamin J; Babbitt, Patricia C

Holliday, Gemma L; Brown, Shoshana D; Mischel, David; Polacco, Benjamin J; Babbitt, Patricia C.

Afiliação

Holliday GL; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.
Brown SD; Present Address: Medicines Discovery Catapult, Mereside, Alderley Park, Alderley Edge SK10 4TG, UK.
Mischel D; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.
Polacco BJ; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.
Babbitt PC; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, 1700 4th Street, CA 94143, USA.

Database (Oxford) ; 20202020 01 01.

Article em En | MEDLINE | ID: mdl-32449511

Assuntos

Biologia Computacional/métodos; Bases de Dados de Proteínas; Enzimas; Enzimas/química; Enzimas/classificação; Enzimas/fisiologia; Anotação de Sequência Molecular; Relação Estrutura-Atividade

Palavras-chave

Comparison of enzyme classification systems; Enzyme classification systems; Enzyme function; Evolution- versus reaction-based enzyme classification; Functional annotation; Structurefunction relationships; Structurereaction relationships

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biologia Computacional / Bases de Dados de Proteínas / Enzimas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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