How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches.
Adv Exp Med Biol
; 1239: 153-181, 2020.
Article
em En
| MEDLINE
| ID: mdl-32451859
ABSTRACT
Myosin 5a is a two-headed myosin that functions as a cargo transporter in cells. To accomplish this task it has evolved several unique structural and kinetic features that allow it to move processively as a single molecule along actin filaments. A plethora of biophysical techniques have been used to elucidate the detailed mechanism of its movement along actin filaments in vitro. This chapter describes how this mechanism was deduced.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Miosinas
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Imagem Individual de Molécula
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Movimento
Limite:
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article