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Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling.
Liu, Xiaomei I; Momper, Jeremiah D; Rakhmanina, Natella Y; Green, Dionna J; Burckart, Gilbert J; Cressey, Tim R; Mirochnick, Mark; Best, Brookie M; van den Anker, John N; Dallmann, André.
Afiliação
  • Liu XI; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA. rph5862@gmail.com.
  • Momper JD; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
  • Rakhmanina NY; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA.
  • Green DJ; Elizabeth Glaser Pediatric AIDS Foundation, Washington, DC, USA.
  • Burckart GJ; Office of Pediatric Therapeutics, US Food and Drug Administration, Silver Spring, MD, USA.
  • Cressey TR; Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, MD, USA.
  • Mirochnick M; PHPT/IRD 174, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
  • Best BM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • van den Anker JN; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
  • Dallmann A; Boston University, School of Medicine, Boston, MA, USA.
Clin Pharmacokinet ; 59(11): 1433-1450, 2020 11.
Article em En | MEDLINE | ID: mdl-32451908
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Piperazinas / Piridonas / Infecções por HIV / Inibidores de Integrase de HIV / Raltegravir Potássico / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Piperazinas / Piridonas / Infecções por HIV / Inibidores de Integrase de HIV / Raltegravir Potássico / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Ano de publicação: 2020 Tipo de documento: Article