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Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator.
Nudischer, Ramona; Renggli, Kasper; Bertinetti-Lapatki, Cristina; Hoflack, Jean-Christophe; Flint, Nicholas; Sewing, Sabine; Pedersen, Lykke; Schadt, Simone; Higgins, Larry G; Vardy, Audrey; Lenz, Barbara; Gand, Laurent; Boess, Franziska; Elcombe, Barbara M; Hierlemann, Andreas; Roth, Adrian B.
Afiliação
  • Nudischer R; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Renggli K; Bioengineering Laboratory, Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Bertinetti-Lapatki C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Hoflack JC; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Flint N; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Sewing S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Pedersen L; Roche Pharma Research and Early Development, Roche Innovation Center Copenhagen, 2970 Hørsholm, Denmark.
  • Schadt S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Higgins LG; CXR Biosciences Ltd, Dundee DD1 5JJ, Scotland, UK.
  • Vardy A; CXR Biosciences Ltd, Dundee DD1 5JJ, Scotland, UK.
  • Lenz B; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Gand L; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Boess F; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Elcombe BM; CXR Biosciences Ltd, Dundee DD1 5JJ, Scotland, UK.
  • Hierlemann A; Bioengineering Laboratory, Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Roth AB; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
Toxicol Sci ; 176(2): 329-342, 2020 08 01.
Article em En | MEDLINE | ID: mdl-32458970
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Receptores de Esteroides / Receptores Citoplasmáticos e Nucleares / Imidazóis Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Receptores de Esteroides / Receptores Citoplasmáticos e Nucleares / Imidazóis Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article