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Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival.
Schultz, Michael D; Dadali, Tulin; Jacques, Sylvain A; Muller-Steffner, Hélène; Foote, Jeremy B; Sorci, Leonardo; Kellenberger, Esther; Botta, Davide; Lund, Frances E.
Afiliação
  • Schultz MD; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Dadali T; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Jacques SA; Laboratoire d'Innovation Thérapeutique, LIT UMR 7200 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France.
  • Muller-Steffner H; Laboratoire des Systèmes Chimiques Fonctionnels, CAMB UMR 7199 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France.
  • Foote JB; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Sorci L; Department of Materials, Environmental Sciences and Urban Planning, Division of Bioinformatics and Biochemistry, Polytechnic University of Marche, Ancona, Italy.
  • Kellenberger E; Laboratoire d'Innovation Thérapeutique, LIT UMR 7200 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France.
  • Botta D; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Lund FE; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
PLoS Pathog ; 16(5): e1008539, 2020 05.
Article em En | MEDLINE | ID: mdl-32459815
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Schistosoma mansoni / Esquistossomose mansoni / Interações Hospedeiro-Parasita / NAD Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Schistosoma mansoni / Esquistossomose mansoni / Interações Hospedeiro-Parasita / NAD Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article