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Hepatic NADH reductive stress underlies common variation in metabolic traits.
Goodman, Russell P; Markhard, Andrew L; Shah, Hardik; Sharma, Rohit; Skinner, Owen S; Clish, Clary B; Deik, Amy; Patgiri, Anupam; Hsu, Yu-Han H; Masia, Ricard; Noh, Hye Lim; Suk, Sujin; Goldberger, Olga; Hirschhorn, Joel N; Yellen, Gary; Kim, Jason K; Mootha, Vamsi K.
Afiliação
  • Goodman RP; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Markhard AL; Liver Center, Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.
  • Shah H; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Sharma R; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Skinner OS; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Clish CB; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Deik A; Broad Institute, Cambridge, MA, USA.
  • Patgiri A; Broad Institute, Cambridge, MA, USA.
  • Hsu YH; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Masia R; Broad Institute, Cambridge, MA, USA.
  • Noh HL; Departments of Pediatrics and Genetics, Harvard Medical School, Boston, MA, USA.
  • Suk S; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.
  • Goldberger O; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Hirschhorn JN; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.
  • Yellen G; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
  • Kim JK; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
  • Mootha VK; Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.
Nature ; 583(7814): 122-126, 2020 07.
Article em En | MEDLINE | ID: mdl-32461692
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Fígado / NAD Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Fígado / NAD Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article