Novel trial strategies to enhance the relevance, efficiency, effectiveness, and impact of nephrology research.
Kidney Int
; 98(3): 572-578, 2020 09.
Article
em En
| MEDLINE
| ID: mdl-32464216
ABSTRACT
Randomized controlled trials (RCTs) are considered the gold standard for evaluating the effectiveness of interventions. However, criticisms of traditional designs are that they can be inefficient, inflexible, expensive, and conducted in a manner disconnected from real-life clinical practice. Novel strategies and approaches are being utilized to overcome these limitations, including comprehensive consumer engagement, core outcome sets, novel trial designs, streamlined data collection, cost-effectiveness and return on investment evaluations, knowledge dissemination plans, and impact evaluation. These strategies can be implemented at the design, conduct, implementation, and dissemination stages of the trial process. This review aims to provide an overview of these strategies and approaches to improve the relevance, efficiency, effectiveness, and impact of nephrology research.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nefrologia
Tipo de estudo:
Clinical_trials
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article