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Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
Ernst, Justin T; Thompson, Peggy A; Nilewski, Christian; Sprengeler, Paul A; Sperry, Samuel; Packard, Garrick; Michels, Theodore; Xiang, Alan; Tran, Chinh; Wegerski, Christopher J; Eam, Boreth; Young, Nathan P; Fish, Sarah; Chen, Joan; Howard, Haleigh; Staunton, Jocelyn; Molter, Jolene; Clarine, Jeff; Nevarez, Andres; Chiang, Gary G; Appleman, Jim R; Webster, Kevin R; Reich, Siegfried H.
Afiliação
  • Ernst JT; Inception Therapeutics, 6175 Nancy Ridge Drive, San Diego, California 92121, United States.
  • Thompson PA; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Nilewski C; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Sprengeler PA; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Sperry S; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Packard G; Inception Therapeutics, 6175 Nancy Ridge Drive, San Diego, California 92121, United States.
  • Michels T; GossamerBio., 3013 Science Park Road, San Diego, California 92121, United States.
  • Xiang A; WuXi AppTec, 6114 Nancy Ridge Drive, San Diego, California 92121, United States.
  • Tran C; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Wegerski CJ; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Eam B; Calporta Therapeutics, 11099 North Torrey Poines Rd., La Jolla, California 92037, United States.
  • Young NP; Casma Therapeutics, 400 Technology Square, Cambridge, California 02139, United States.
  • Fish S; Plexium, Inc., 11585 Sorrento Valley Rd., San Diego, California 92121, United States.
  • Chen J; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Howard H; Providence Portland Medical Center, 4805 NE Glisan Street, Portland, Oregon 97213, United States.
  • Staunton J; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Molter J; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Clarine J; GossamerBio., 3013 Science Park Road, San Diego, California 92121, United States.
  • Nevarez A; Escient Pharmaceuticals, 10578 Science Center Dr., San Diego, California 92121, United States.
  • Chiang GG; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
  • Appleman JR; Primmune Therapeutics, 3210 Merryfield Row, San Diego, California 92121, United States.
  • Webster KR; Frontier Medicines Corp., 151 Oyster Point Blvd., South San Francisco, California 94080, United States.
  • Reich SH; eFFECTOR Therapeutics, 11180 Roselle Street, San Diego, California 92121, United States.
J Med Chem ; 63(11): 5879-5955, 2020 06 11.
Article em En | MEDLINE | ID: mdl-32470302
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Desenho de Fármacos / Fator de Iniciação 4A em Eucariotos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Desenho de Fármacos / Fator de Iniciação 4A em Eucariotos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article