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Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening.
Hou, Hui; Yang, Ruirui; Liu, Xiaohong; Wu, Xiaolong; Zhang, Sulin; Chen, Kaixian; Zheng, Mingyue.
Afiliação
  • Hou H; School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of
  • Yang R; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; Shanghai Institute for Advanced Immunochemical St
  • Liu X; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; Shanghai Institute for Advanced Immunochemical St
  • Wu X; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Pharmacy, East China University of Scie
  • Zhang S; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: slzhang@simm.ac.cn.
  • Chen K; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: kxchen@simm.ac.cn.
  • Zheng M; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: myzheng@simm.ac.cn.
Bioorg Chem ; 100: 103958, 2020 07.
Article em En | MEDLINE | ID: mdl-32470762
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinoxalinas / Triazóis / Simulação de Acoplamento Molecular / Proteínas de Membrana Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinoxalinas / Triazóis / Simulação de Acoplamento Molecular / Proteínas de Membrana Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article