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Long non-coding RNA GAS5, by up-regulating PRC2 and targeting the promoter methylation of miR-424, suppresses multiple malignant phenotypes of glioma.
Jin, Chen; Zhao, Jie; Zhang, Zhi-Ping; Wu, Ming; Li, Jian; Xiao, Ge-Lei; Liu, Bo; Liao, Yu-Xiang; Liu, Jing-Ping.
Afiliação
  • Jin C; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Zhao J; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Zhang ZP; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Wu M; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Li J; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Xiao GL; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Liu B; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Liao YX; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China.
  • Liu JP; Department of Neurosurgery, Xiangya Hospital, Central South University, No.87, Xiangya Road, Changsha, 410008, P.R. China. ljping@csu.edu.cn.
J Neurooncol ; 148(3): 529-543, 2020 Jul.
Article em En | MEDLINE | ID: mdl-32472311
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Regiões Promotoras Genéticas / Metilação de DNA / MicroRNAs / Complexo Repressor Polycomb 2 / RNA Longo não Codificante / Glioma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Regiões Promotoras Genéticas / Metilação de DNA / MicroRNAs / Complexo Repressor Polycomb 2 / RNA Longo não Codificante / Glioma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article