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A systematic review of secretory carcinoma of the salivary gland: where are we?
Alves, Lísia Daltro Borges; de Melo, Andreia Cristina; Farinha, Thayana Alves; de Lima Araujo, Luiz Henrique; Thiago, Leandro de Souza; Dias, Fernando Luiz; Antunes, Héliton Spíndola; Amaral Eisenberg, Ana Lucia; Santos Thuler, Luiz Claudio; Cohen Goldemberg, Daniel.
Afiliação
  • Alves LDB; National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • de Melo AC; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Farinha TA; Scientific Initiation Student, Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • de Lima Araujo LH; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Thiago LS; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Dias FL; Head and Neck Surgery Service, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Antunes HS; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Amaral Eisenberg AL; Pathology Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Santos Thuler LC; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA).
  • Cohen Goldemberg D; Clinical Research Division, National Cancer Institute of Brazil, Rio de Janeiro, Brazil (INCA). Electronic address: daniel.cohen@inca.gov.br.
Oral Surg Oral Med Oral Pathol Oral Radiol ; 132(4): e143-e152, 2021 10.
Article em En | MEDLINE | ID: mdl-32493686
OBJECTIVE: The aim of this systematic review was to describe the epidemiology, diagnostic criteria, differential diagnosis, treatment, prognostic factors, and treatment outcomes of secretory carcinoma. STUDY DESIGN: A comprehensive search of Lilacs, PubMed, Science Direct, and Web of Science databases was conducted to identify all case reports, letter to the editor, and histopathologic reclassifications regarding salivary gland secretory carcinoma published in English, Spanish, French, and Portuguese. RESULTS: The final analysis included 119 studies, which totaled 642 secretory carcinoma diagnoses, with 239 case reports and 403 diagnostic reclassifications, mostly in the United States. The age range was 5 to 87 years, and cases were predominantly in males (58.7%) and mostly affecting the parotid glands (73.7%). The disease usually presents as a slow-growing, painless mass. The main differential diagnosis is acinic cell carcinoma, and the tumor is usually treated with surgery. The prognosis is considered favorable, although there have been reports of local recurrences, distant metastases, and deaths. CONCLUSIONS: It is important that clinicians become aware of this salivary gland neoplasm and report clinical data, clinical course, management and long-term follow-up. There is an urgent need to conduct more clinical trials, especially on tropomyosin receptor kinase (TRK) inhibitors and other potential target therapy modalities.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias das Glândulas Salivares / Carcinoma / Carcinoma de Células Acinares Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias das Glândulas Salivares / Carcinoma / Carcinoma de Células Acinares Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article