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Intranasal delivery of mesenchymal stem cell-derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease.
Losurdo, Morris; Pedrazzoli, Matteo; D'Agostino, Claudia; Elia, Chiara A; Massenzio, Francesca; Lonati, Elena; Mauri, Mario; Rizzi, Laura; Molteni, Laura; Bresciani, Elena; Dander, Erica; D'Amico, Giovanna; Bulbarelli, Alessandra; Torsello, Antonio; Matteoli, Michela; Buffelli, Mario; Coco, Silvia.
Afiliação
  • Losurdo M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Pedrazzoli M; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
  • D'Agostino C; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Elia CA; Laboratory of Pharmacology and Brain Pathology, Neuro Center, Humanitas Clinical and Research Center-IRCCS, Rozzano (MI), Italy.
  • Massenzio F; CNR, Institute of Neuroscience, Milano, Italy.
  • Lonati E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
  • Mauri M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Rizzi L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Molteni L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Bresciani E; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Dander E; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • D'Amico G; Centro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
  • Bulbarelli A; Centro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
  • Torsello A; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Matteoli M; NeuroMI-Milan Center for Neuroscience, University of Milano-Bicocca, Milano (MI), Italy.
  • Buffelli M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
  • Coco S; Laboratory of Pharmacology and Brain Pathology, Neuro Center, Humanitas Clinical and Research Center-IRCCS, Rozzano (MI), Italy.
Stem Cells Transl Med ; 9(9): 1068-1084, 2020 09.
Article em En | MEDLINE | ID: mdl-32496649
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunomodulação / Células-Tronco Mesenquimais / Doença de Alzheimer / Vesículas Extracelulares / Neuroproteção Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunomodulação / Células-Tronco Mesenquimais / Doença de Alzheimer / Vesículas Extracelulares / Neuroproteção Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article