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Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma.
Ali, Wesam; Spengler, Gabriella; Kincses, Annamária; Nové, Márta; Battistelli, Cecilia; Latacz, Gniewomir; Starek, Malgorzata; Dabrowska, Monika; Honkisz-Orzechowska, Ewelina; Romanelli, Annalisa; Rasile, Manuela Monica; Szymanska, Ewa; Jacob, Claus; Zwergel, Clemens; Handzlik, Jadwiga.
Afiliação
  • Ali W; Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Kraków, Poland; Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B 2.1, D-66123, Saarbruecken, Germany.
  • Spengler G; Institute of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, H-6720, Szeged, Hungary.
  • Kincses A; Institute of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, H-6720, Szeged, Hungary.
  • Nové M; Institute of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Dóm tér 10, H-6720, Szeged, Hungary.
  • Battistelli C; Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Department of Molecular Medicine, "Department of Excellence 2018-2022", Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Kraków, Poland.
  • Starek M; Department of Inorganic Chemistry, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Cracow, Poland.
  • Dabrowska M; Department of Inorganic Chemistry, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Cracow, Poland.
  • Honkisz-Orzechowska E; Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Kraków, Poland.
  • Romanelli A; Department of Drug Chemistry and Technologies, "Department of Excellence 2018-2022", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Rasile MM; Department of Drug Chemistry and Technologies, "Department of Excellence 2018-2022", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Szymanska E; Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Kraków, Poland.
  • Jacob C; Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B 2.1, D-66123, Saarbruecken, Germany. Electronic address: c.jacob@mx.uni-saarland.de.
  • Zwergel C; Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B 2.1, D-66123, Saarbruecken, Germany; Department of Drug Chemistry and Technologies, "Department of Excellence 2018-2022", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy; Department of Precision
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688, Kraków, Poland. Electronic address: j.handzlik@uj.edu.pl.
Eur J Med Chem ; 200: 112435, 2020 Aug 15.
Article em En | MEDLINE | ID: mdl-32505850
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma de Células T / Compostos Organosselênicos / Éteres / Descoberta de Drogas / Hidantoínas / Antineoplásicos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma de Células T / Compostos Organosselênicos / Éteres / Descoberta de Drogas / Hidantoínas / Antineoplásicos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article