Clinical Characteristics of Hospitalized Individuals Dying With COVID-19 by Age Group in Italy.
J Gerontol A Biol Sci Med Sci
; 75(9): 1796-1800, 2020 09 16.
Article
em En
| MEDLINE
| ID: mdl-32506122
ABSTRACT
BACKGROUND:
Aim of the present study is to describe characteristics of COVID-19-related deaths and to compare the clinical phenotype and course of COVID-19-related deaths occurring in adults (<65 years) and older adults (≥65 years).METHOD:
Medical charts of 3,032 patients dying with COVID-19 in Italy (368 aged < 65 years and 2,664 aged ≥65 years) were revised to extract information on demographics, preexisting comorbidities, and in-hospital complications leading to death.RESULTS:
Older adults (≥65 years) presented with a higher number of comorbidities compared to those aged <65 years (3.3 ± 1.9 vs 2.5 ± 1.8, p < .001). Prevalence of ischemic heart disease, atrial fibrillation, heart failure, stroke, hypertension, dementia, COPD, and chronic renal failure was higher in older patients (≥65 years), while obesity, chronic liver disease, and HIV infection were more common in younger adults (<65 years); 10.9% of younger patients (<65 years) had no comorbidities, compared to 3.2% of older patients (≥65 years). The younger adults had a higher rate of non-respiratory complications than older patients, including acute renal failure (30.0% vs 20.6%), acute cardiac injury (13.5% vs 10.3%), and superinfections (30.9% vs 9.8%).CONCLUSIONS:
Individuals dying with COVID-19 present with high levels of comorbidities, irrespective of age group, but a small proportion of deaths occur in healthy adults with no preexisting conditions. Non-respiratory complications are common, suggesting that the treatment of respiratory conditions needs to be combined with strategies to prevent and mitigate the effects of non-respiratory complications.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Doenças Cardiovasculares
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Infecções por Coronavirus
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Demência
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Pandemias
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Falência Renal Crônica
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prevalence_studies
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Prognostic_studies
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article