Higher body mass index at ages 16 to 20 years is associated with increased risk of a multiple sclerosis diagnosis in subsequent adulthood among men.
Mult Scler
; 27(1): 147-150, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-32507076
ABSTRACT
BACKGROUND:
Evidence for the association between body mass index (BMI) and multiple sclerosis (MS) among men remains mixed. OBJECTIVE ANDMETHODS:
Swedish military conscription and other registers identified MS after age of 20 years and BMI at ages 16-20 years (N = 744,548).RESULTS:
Each unit (kg/m2) BMI increase was associated with greater MS risk (hazard ratio and 95% confidence interval = 1.034, 1.016-1.053), independent of physical fitness (1.021, 1.001-1.042). Categorised, overweight and obesity were associated with statistically significant raised MS risk compared to normal weight, but not after adjustment for physical fitness.CONCLUSION:
MS risk rises with increasing BMI, across the entire BMI range.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Esclerose Múltipla
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Humans
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Male
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article