Tramadol exposure upregulated apoptosis, inflammation and autophagy in PC12 cells and rat's striatum: An in vitro- in vivo approach.

Soltani, Reza; Boroujeni, Mahdi Eskandarian; Aghajanpour, Fakhroddin; Khatmi, Aysan; Ezi, Samira; Mirbehbahani, Seyed Hamidreza; Abdollahifar, Mohammad-Amin; Akhlaghpasand, Mohamadhosein; Aliaghaei, Abbas; Heidari, Mohammad-Hasan

Soltani, Reza; Boroujeni, Mahdi Eskandarian; Aghajanpour, Fakhroddin; Khatmi, Aysan; Ezi, Samira; Mirbehbahani, Seyed Hamidreza; Abdollahifar, Mohammad-Amin; Akhlaghpasand, Mohamadhosein; Aliaghaei, Abbas; Heidari, Mohammad-Hasan.

Afiliação

Soltani R; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Boroujeni ME; Department of Human Molecular Genetics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland.
Aghajanpour F; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khatmi A; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ezi S; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mirbehbahani SH; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abdollahifar MA; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Akhlaghpasand M; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aliaghaei A; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: aghaei60@gmail.com.
Heidari MH; Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: heidari34@gmail.com.

J Chem Neuroanat ; 109: 101820, 2020 11.

Article em En | MEDLINE | ID: mdl-32526246

Assuntos

Analgésicos Opioides/farmacologia; Apoptose/efeitos dos fármacos; Autofagia/efeitos dos fármacos; Corpo Estriado/efeitos dos fármacos; Inflamação/metabolismo; Tramadol/farmacologia; Animais; Sobrevivência Celular/efeitos dos fármacos; Corpo Estriado/metabolismo; Masculino; Neurônios/efeitos dos fármacos; Neurônios/metabolismo; Células PC12; Ratos; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Neurodegeneration; Neuroinflammatory; Striatum; Tramadol

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Tramadol / Apoptose / Corpo Estriado / Analgésicos Opioides / Inflamação Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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