Iodine-Catalyzed Aerobic Oxidation of Spirovinylcyclopropyl Oxindoles to Form Spiro-1,2-dioxolanes Diastereoselectively.
J Org Chem
; 85(14): 9386-9395, 2020 07 17.
Article
em En
| MEDLINE
| ID: mdl-32527084
ABSTRACT
A novel method of iodine-catalyzed aerobic oxidation with spirovinylcyclopropyl oxindoles under mild conditions has been described. A series of spiro-1,2-dioxolanes were prepared in good to excellent yields and considerable diastereoselectivities. The new approach is operationally simple, scalable, and tolerant of various functional groups.
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MEDLINE
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En
Ano de publicação:
2020
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Article