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Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts.
Doggett, J Stone; Schultz, Tracey; Miller, Alyssa J; Bruzual, Igor; Pou, Sovitj; Winter, Rolf; Dodean, Rozalia; Zakharov, Lev N; Nilsen, Aaron; Riscoe, Michael K; Carruthers, Vern B.
Afiliação
  • Doggett JS; Division of Infectious Diseases, Oregon Health and Science University School of Medicine, Portland, Oregon, USA doggettj@ohsu.edu.
  • Schultz T; Department of Hospital and Specialty Medicine, Veterans Affairs Portland Health Care System, Portland, Oregon, USA.
  • Miller AJ; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Bruzual I; Program in Cell and Molecular Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Pou S; Department of Internal Medicine, Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
  • Winter R; Department of Hospital and Specialty Medicine, Veterans Affairs Portland Health Care System, Portland, Oregon, USA.
  • Dodean R; Department of Hospital and Specialty Medicine, Veterans Affairs Portland Health Care System, Portland, Oregon, USA.
  • Zakharov LN; Department of Hospital and Specialty Medicine, Veterans Affairs Portland Health Care System, Portland, Oregon, USA.
  • Nilsen A; Department of Hospital and Specialty Medicine, Veterans Affairs Portland Health Care System, Portland, Oregon, USA.
  • Riscoe MK; Department of Chemistry, University of Oregon, Eugene, Oregon, USA.
  • Carruthers VB; Division of Infectious Diseases, Oregon Health and Science University School of Medicine, Portland, Oregon, USA.
Article em En | MEDLINE | ID: mdl-32540978

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma / Pró-Fármacos / Toxoplasmose Animal / Quinolonas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma / Pró-Fármacos / Toxoplasmose Animal / Quinolonas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article