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The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation.
Shimizu, Takanobu; Nakamura, Takeshi; Inaba, Hironori; Iwasa, Hiroaki; Maruyama, Junichi; Arimoto-Matsuzaki, Kyoko; Nakata, Takao; Nishina, Hiroshi; Hata, Yutaka.
Afiliação
  • Shimizu T; Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Nakamura T; Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Inaba H; Department of Cell Biology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan.
  • Iwasa H; Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan hiwammch@tmd.ac.jp yuhammch@tmd.ac.jp.
  • Maruyama J; Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Arimoto-Matsuzaki K; Department of Medical Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Nakata T; Department of Cell Biology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan.
  • Nishina H; Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo, Japan.
  • Hata Y; Department of Developmental and Regenerative Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
J Biol Chem ; 295(32): 11214-11230, 2020 08 07.
Article em En | MEDLINE | ID: mdl-32554467
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Proteínas ras / Proteínas Adaptadoras de Transdução de Sinal / Proteínas Proto-Oncogênicas c-mdm2 / Proteínas Reguladoras de Apoptose Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Proteínas ras / Proteínas Adaptadoras de Transdução de Sinal / Proteínas Proto-Oncogênicas c-mdm2 / Proteínas Reguladoras de Apoptose Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article