Meta-analysis of transcriptomic variation in T-cell populations reveals both variable and consistent signatures of gene expression and splicing.

Radens, Caleb M; Blake, Davia; Jewell, Paul; Barash, Yoseph; Lynch, Kristen W

Radens, Caleb M; Blake, Davia; Jewell, Paul; Barash, Yoseph; Lynch, Kristen W.

Afiliação

Radens CM; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Blake D; Immunology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Jewell P; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Barash Y; Department of Computer Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Lynch KW; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

RNA ; 26(10): 1320-1333, 2020 10.

Article em En | MEDLINE | ID: mdl-32554554

Assuntos

Linfócitos T CD4-Positivos/fisiologia; Expressão Gênica/genética; Splicing de RNA/genética; Subpopulações de Linfócitos T/fisiologia; Transcriptoma/genética; Adulto; Células Cultivadas; Citocinas/genética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade

Palavras-chave

T cells; Th1; Th17; Th2; Treg; alternative splicing; transcriptomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Expressão Gênica / Splicing de RNA / Subpopulações de Linfócitos T / Transcriptoma Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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