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SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.
Xue, Yibo; Zhu, Xianbing; Meehan, Brian; Venneti, Sriram; Martinez, Daniel; Morin, Geneviève; Maïga, Rayelle I; Chen, Hongbo; Papadakis, Andreas I; Johnson, Radia M; O'Sullivan, Maureen J; Erdreich-Epstein, Anat; Gotlieb, Walter H; Park, Morag; Judkins, Alexander R; Pelletier, Jerry; Foulkes, William D; Rak, Janusz; Huang, Sidong.
Afiliação
  • Xue Y; Department of Biochemistry, McGill University, Montreal, Canada.
  • Zhu X; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Meehan B; Department of Biochemistry, McGill University, Montreal, Canada.
  • Venneti S; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Martinez D; Department of Pediatrics, McGill University, and Research Institute of McGill University Health Centre, Montreal Children's Hospital, Montreal, Canada.
  • Morin G; Pathology and Neuropathology, University of Michigan Medical School, Ann Arbor, MI, USA.
  • Maïga RI; Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA.
  • Chen H; Department of Biochemistry, McGill University, Montreal, Canada.
  • Papadakis AI; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Johnson RM; Department of Biochemistry, McGill University, Montreal, Canada.
  • O'Sullivan MJ; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Erdreich-Epstein A; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, PR China.
  • Gotlieb WH; Department of Biochemistry, McGill University, Montreal, Canada.
  • Park M; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Judkins AR; Department of Biochemistry, McGill University, Montreal, Canada.
  • Pelletier J; Goodman Cancer Research Centre, McGill University, Montreal, Canada.
  • Foulkes WD; School of Medicine, University of Dublin, Trinity College, Dublin, Ireland.
  • Rak J; Children's Health Ireland at Crumlin, Dublin, Ireland.
  • Huang S; Departments of Pediatrics and Pathology, The Saban Research Institute at Children's Hospital Los Angeles and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
J Pathol ; 252(1): 77-87, 2020 09.
Article em En | MEDLINE | ID: mdl-32558936
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Teratoma / Proteínas / Regulação Neoplásica da Expressão Gênica / Tumor Rabdoide / Ciclina D1 / Proteína SMARCB1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Teratoma / Proteínas / Regulação Neoplásica da Expressão Gênica / Tumor Rabdoide / Ciclina D1 / Proteína SMARCB1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article