Secondary metabolites isolated from Agrimonia pilosa Ledeb.
Nat Prod Res
; 36(1): 263-270, 2022 Jan.
Article
em En
| MEDLINE
| ID: mdl-32567424
A pilot study on the ethanol extracts of Agrimonia pilosa found to have anti-α-glucosidase and anti-inflammatory activities. Subsequent chemical study afforded a new phenylethyl isocoumarin glycoside (1) and eight known compounds (2-9). The structure of 1 was elucidated by comprehensive spectroscopic analysis and chemical transformations. All compounds showed modest α-glucosidase inhibitory activity (IC50 values ranging from 36.8 to 210.7 µM), which was lower than that of the positive control acarbose (IC50=301.9 µM). Those compounds except inactive compounds 3 and 6 showed weak anti-inflammatory activity.[Formula: see text].
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MEDLINE
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Agrimonia
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En
Ano de publicação:
2022
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Article